{"id":34017,"date":"2025-07-07T07:17:00","date_gmt":"2025-09-10T03:32:55","guid":{"rendered":"https:\/\/www.iff.com\/health-sciences\/our-products\/howaru-lpc-37\/"},"modified":"2026-03-06T11:45:56","modified_gmt":"2026-03-06T16:45:56","slug":"howaru-lpc-37","status":"publish","type":"our_products","link":"https:\/\/www.iff.com\/es\/health-sciences\/our-products\/howaru-lpc-37\/","title":{"rendered":"HOWARU\u00ae Lpc-37\u00ae"},"content":{"rendered":"<div class=\"m-block  gt gb simple-cards-v2 media-cover l-content-1\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\"\n\t\tstyle=\"; --l-block-col: 4;--l-block-gap-vertical: 30px;--l-block-gap-horizontal: 30px;\">\n\n        <div class=\"l-heading container text-left l-heading-v2\">\n\n\t        <div class=\"l-heading__content\">\n\t                <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Lpc-37\u00ae BLENDS<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Learn more about IFF Health Sciences&#8217; Lpc-37\u00ae blends.<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \t        <\/div>\n        <\/div>\n\n\t\t<div class=\"l-rcbl l-rcbl-v1 -col4\">\n\n\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"l-rcbl__col\">\n\t\t\t\t\t\t\n<article class=\"c-block  c-block-v1 is-vertical text-left align-bottom\" style=\"--c-block-gap-vertical:25px;--c-block-gap-horizontal:25px;\">\n\n\t        <a class=\"c-block__link-full\" href=\"https:\/\/www.iff.com\/es\/health-sciences\/our-products\/howaru-calm\/\" title=\"HOWARU\u00ae Calm\" ><\/a>\n\t\n\t        <div class=\"c-block__media\">\n\t\t\t\n\t\t\t\t<div class=\"c-image\">\n\t\t<figure class=\"c-image__media c-image__primary\">\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/09\/IFF_HS_Our-Products_HOWARU-Calm_Cropped3-400x184.jpg\"  alt=\"IFF_HS_Our-Products_HOWARU-Calm_Cropped3\" width=\"400\" height=\"184\"\/>\t\t\t\t\t<\/figure>\n\t<\/div>\n\t        <\/div>\n\t\n    <div class=\"c-block__body\" >\n\n\t\t\n\t\t\t\t\t<h3  class=\"c-block__title\">HOWARU\u00ae Calm<\/h3>\t\t\n\t    <div class=\"c-block__content\">\n\t\t    <div>\n\t\t\t\t\t\t\t    \n\t\t\t\t\t\t    <\/div>\n\t    <\/div>\n\n    <\/div>\n\n<\/article>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"l-rcbl__col\">\n\t\t\t\t\t\t\n<article class=\"c-block  c-block-v1 is-vertical text-left align-bottom\" style=\"--c-block-gap-vertical:25px;--c-block-gap-horizontal:25px;\">\n\n\t        <a class=\"c-block__link-full\" href=\"https:\/\/www.iff.com\/es\/health-sciences\/our-products\/howaru-gi-complete\/\" title=\"HOWARU\u00ae GI Complete\" ><\/a>\n\t\n\t        <div class=\"c-block__media\">\n\t\t\t\n\t\t\t\t<div class=\"c-image\">\n\t\t<figure class=\"c-image__media c-image__primary\">\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/09\/d068b70b62be0324dc4c23d5d77a3a96c39d4691_cropped3-400x115.jpg\"  alt=\"d068b70b62be0324dc4c23d5d77a3a96c39d4691_cropped3\" width=\"400\" height=\"115\"\/>\t\t\t\t\t<\/figure>\n\t<\/div>\n\t        <\/div>\n\t\n    <div class=\"c-block__body\" >\n\n\t\t\n\t\t\t\t\t<h3  class=\"c-block__title\">HOWARU\u00ae GI Complete<\/h3>\t\t\n\t    <div class=\"c-block__content\">\n\t\t    <div>\n\t\t\t\t\t\t\t    \n\t\t\t\t\t\t    <\/div>\n\t    <\/div>\n\n    <\/div>\n\n<\/article>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"l-rcbl__col\">\n\t\t\t\t\t\t\n<article class=\"c-block  c-block-v1 is-vertical text-left align-bottom\" style=\"--c-block-gap-vertical:25px;--c-block-gap-horizontal:25px;\">\n\n\t        <a class=\"c-block__link-full\" href=\"https:\/\/www.iff.com\/es\/health-sciences\/our-products\/howaru-restore\/\" title=\"HOWARU\u00ae Restore\" ><\/a>\n\t\n\t        <div class=\"c-block__media\">\n\t\t\t\n\t\t\t\t<div class=\"c-image\">\n\t\t<figure class=\"c-image__media c-image__primary\">\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/09\/Howaru-Restore-Cropped2-400x130.jpg\"  alt=\"Howaru-Restore-Cropped2\" width=\"400\" height=\"130\"\/>\t\t\t\t\t<\/figure>\n\t<\/div>\n\t        <\/div>\n\t\n    <div class=\"c-block__body\" >\n\n\t\t\n\t\t\t\t\t<h3  class=\"c-block__title\">HOWARU\u00ae Restore<\/h3>\t\t\n\t    <div class=\"c-block__content\">\n\t\t    <div>\n\t\t\t\t\t\t\t    \n\t\t\t\t\t\t    <\/div>\n\t    <\/div>\n\n    <\/div>\n\n<\/article>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white --decor-blue --pattern-v4 --decor --stats-type2 txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Lpc-37\u00ae CLINICAL STUDIES &#038; PUBLICATIONS<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Lpc-37\u00ae has been cited in more than 65 scientific publications, including more than 47 clinical trials. It has a long history of safe use, is well-suited for intestinal survival, and has strong adhesion to intestinal cell lines and pathogen inhibition.\u00b3\u207b\u2074<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-accordion  gt gb style-v2 l-two-cols\"  >\n\n\t\n\t\n\t<div class=\"m-accordion__container container\" style=\"\">\n\n        <div class=\"l-heading\">\n                <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h4  class=\"c-heading__title\">Health Benefit Areas<\/h4>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Each strain\u2019s health benefits are supported by recommended daily doses and peer-reviewed clinical studies.<\/p>\n<p><strong>Click on a Health Benefit to see more studies and learn more.<\/strong><\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\t\t\t        <\/div>\n\n\t\t<div class=\"l-accordion l-accordion-v1 js-acc-wrapper icons-arrows\" style=\"--c-block-gl: 0px;--c-block-gr: 0px;--c-block-gt: 0px;--c-block-gb: 0px;\"  data-animation=\"js\">\n\n\t\t\t\n\t\t\t\t<div class=\"c-accordion c-accordion-v1\">\n\n\t\t\t\t\t\n                        \n\t\t\t\t\t\t\n<div class=\"c-accordion__item js-acc-item is-active\">\n\t\t\t\n\t\t<h3  class=\"c-accordion__title-wrap -h3\">\t\t<button class=\"js-acc-button c-accordion__title\">\n\t\t\t\n\t\t\t\n\t\t\tBrain Health\t\t<\/button>\n\t\t<\/h3>\t\n\t<div class=\"js-acc-content\">\n\t\t\t\t\t\t\t<div class=\"c-accordion__content\">\n\t\t\t\t<div class=\"is-wysiwyg\">\n\t\t\t\t\t<div class='v1-column'>\n<p><strong>Supporting Daily Dose: <\/strong>17B CFU Lpc-37\u00ae<\/p>\n<p><strong>Study Reference: <\/strong><u><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352289520300679?via%3Dihub\" target=\"_blank\">Patterson E, et al. Neurobiol Stress. 2020;13:100277.<\/a><\/u><\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t    <div class=\"c-block__btn\">\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/health-benefits\/brain-health\/\"  class=\"c-btn -normal -primary has-icon icon-right\"><span class=\"c-btn__txt\">LEARN MORE<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t    <\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\n<\/div>\n\n\t\t\t\t\t\t\n                        \n\t\t\t\t\t\t\n<div class=\"c-accordion__item js-acc-item\">\n\t\t\t\n\t\t<h3  class=\"c-accordion__title-wrap -h3\">\t\t<button class=\"js-acc-button c-accordion__title\">\n\t\t\t\n\t\t\t\n\t\t\tDigestive Health\t\t<\/button>\n\t\t<\/h3>\t\n\t<div class=\"js-acc-content\">\n\t\t\t\t\t\t\t<div class=\"c-accordion__content\">\n\t\t\t\t<div class=\"is-wysiwyg\">\n\t\t\t\t\t<div class='v1-column'>\n<ol>\n<li><strong>Supporting Daily Dose: <\/strong>2B CFU Lpc-37\u00ae\n<p><strong>Study Reference: <\/strong><u><a href=\"https:\/\/www.cabidigitallibrary.org\/doi\/full\/10.5555\/20143400746\" target=\"_blank\">Hemalatha R, et al. EJNF. 2014; 4(4):325-341.<\/a><\/u><\/li>\n<li><strong>Supporting Daily Dose: <\/strong>17B (equal parts) CFU Bl-04\u00ae, NCFM\u00ae, Bi-07\u00ae, Lpc-37\u00ae\n<p><strong>Study Reference: <\/strong><u><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24291194\/\" target=\"_blank\">Ouwehand AC, et al. Vaccine. 2014;32(4):458-463.<\/a><\/u><\/li>\n<li><strong>Supporting Daily Dose: <\/strong>2.5B CFU NCFM\u00ae, 2.5B CFU Lpc-37\u00ae, 2.5B CFU Bl-04\u00ae, 2.5B CFU Bi-07\u00ae, 2B CFU HN019\u2122\n<p><strong>Study Reference: <\/strong><u><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34028393\/\" target=\"_blank\">Harris L, et al. J Clin Gastroenterol. 2022; 56(5):444-451<\/a><\/u><\/li>\n<li><strong>Supporting Daily Dose: <\/strong>10B CFU Total Bi-07\u00ae, Bl-04\u00ae, NCFM\u00ae, Lpc-37\u00ae\n<p><strong>Study Reference: <\/strong><u><a href=\"https:\/\/www.mdpi.com\/2076-2607\/12\/4\/796\" target=\"_blank\">van Zanten G, et al. Microorganisms. 2024; 12(4),796.<\/a><\/u><\/li>\n<\/ol>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t    <div class=\"c-block__btn\">\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/health-benefits\/digestive-health\/\"  class=\"c-btn -normal -primary has-icon icon-right\"><span class=\"c-btn__txt\">LEARN MORE<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t    <\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\n<\/div>\n\n\t\t\t\t\t\t\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<div class=\"m-block  gt gb l-content-simple-1\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-heading text-left l-heading-v1\">\n\n\t\t\t<div class=\"l-heading__content\">\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p><small><strong>References: 1. <\/strong>Ouwehand AC, et al.;Vaccine. 2014\u200b; <strong>2.<\/strong> Patterson E, et al;.Neurobiol Stress. 2020\u200b; <strong>3.<\/strong> Ding WK, et al;,J Food Sci. 2007\u200b; <strong>4.<\/strong> Gibson GR, et al,; Br J Nutr. 2005.<\/small><\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-banner m-banner--small banner-contact order-default\" >\n\n\t\n\t\n\t<div class=\"m-banner__container container-fluid\" style='--columns-ratio: 100%;'>\n\t\t<div class=\"m-banner__media\">\n\t\t\t<picture class=\"m-banner__picture\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1440\" height=\"810\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc.jpg 1440w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-300x169.jpg 300w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-1024x576.jpg 1024w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-768x432.jpg 768w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-400x225.jpg 400w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-200x113.jpg 200w\" sizes=\"auto, (max-width: 1440px) 100vw, 1440px\" \/>\t\t\t\t\t\t\t<\/picture>\n\t\t<\/div>\n\n\t\t<div class=\"m-banner__inner container flex-left style-dark\">\n\n\t\t\t<div class=\"l-banner  l-gt-d l-gb-d\" style=\"\">\n\n\t\t\t\t\n<div class=\"l-banner__text\">\n\t    <div class=\"l-banner__inner text-left\">\n\n        <div class=\"c-heading -h2\">\n\t\t\t\n\t\t\t\t\t\t\t<h2  class=\"c-heading__title\"> How Can We Help?<\/h2>\t\t\t\n\t\t\t        <\/div>\n\n\t\t            <div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t<p>We\u2019d love to talk to you about how our microbiome and bioscience expertise can help you develop, manufacture and deliver solutions that enable people at all life stages to live healthier and happier lives. \u200b<\/p>\n            <\/div>\n\t\t\t\t\n\t\t    <\/div>\n\t\t    <div class=\"c-block__btn\">\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/contact-us\/\" target=\"_blank\" class=\"c-btn -normal -secondary has-icon icon-right\"><span class=\"c-btn__txt\">Contact Us<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/subscribe\/\" target=\"_blank\" class=\"c-btn -normal -secondary has-icon icon-right\"><span class=\"c-btn__txt\">Subscribe<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t\n\t\t\t<a href=\"https:\/\/www.linkedin.com\/showcase\/howaru-premium-probiotics\/\" target=\"_blank\" class=\"c-btn -normal -link has-icon icon-right\"><span class=\"c-btn__txt\">Follow Us<\/span><span class=\"c-btn__ico\"><svg fill=\"none\" height=\"21\" viewbox=\"0 0 23 21\" width=\"23\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path clip-rule=\"evenodd\" d=\"m2.75783 0c-1.66757 0-2.75783 1.05742-2.75783 2.44728 0 1.35918 1.05782 2.44676 2.69387 2.44676h.03163c1.70019 0 2.75825-1.08758 2.75825-2.44676-.03176-1.38986-1.05806-2.44728-2.72592-2.44728zm-2.488059 6.83477h4.874959v14.16473h-4.874994zm12.474729 2.05453s1.7633-2.3867 4.3933-2.3867c3.2071 0 5.6122 2.02465 5.6122 6.3755v8.1219h-4.8745v-7.5778c0-1.9042-.7056-3.2032-2.4696-3.2032-1.3468 0-2.1487.876-2.5013 1.7216-.1286.3028-.1605.7256-.1605 1.1491v7.9103h-4.87483v-14.16497h4.87523z\" fill=\"#99c8ec\" fill-rule=\"evenodd\"\/><\/svg><\/span><\/a>\n\t\t    <\/div>\n\t<\/div>\n\n\n\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t<\/div>\n\n<\/div>","protected":false},"featured_media":34018,"template":"","product_health_benefits":[394,395],"product_type":[390],"class_list":["post-34017","our_products","type-our_products","status-publish","has-post-thumbnail","hentry","product_health_benefits-brain","product_health_benefits-digestive","product_type-probiotic-strain"],"acf":{"full_name":"HOWARU\u00ae Lpc-37\u00ae","latin_name":"HOWARU\u00ae *Lacticaseibacillus paracasei* LPC-37\u00ae","short_description":"HOWARU\u00ae Lpc-37\u00ae supports overall digestive health as well as managing the psychological response to stress.","product_description":"<small><em>Image credits: \u00a9 IFF, Finland, 2021 (FESEM imaging VTT)<\/em><\/small>\r\n\r\nHOWARU\u00ae <em>Lacticaseibacillus paracasei<\/em>\u200b Lpc-37\u00ae can be paired with other strains like NCFM\u00ae, Bi-07\u00ae, and Bl-04\u00ae in our HOWARU\u00ae Restore blend. Together, they support gut health, lessen the days of gut disruption and support overall digestive health.\u00b9 Beyond digestion, Lpc-37\u00ae has been investigated for its impact on managing the psychological response to stress as HOWARU\u00ae Calm.\u00b2 It\u2019s not just about the gut\u2014it\u2019s about holistic wellbeing.","pdf_file":"","product_information":"<ul>\r\n \t<li>126 scientific publications<\/li>\r\n \t<li>50+ clinical trials<\/li>\r\n<\/ul>\r\n<img class=\"alignnone size-medium wp-image-24705\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/09\/HOWARU_VERIFY-Protocol-Quality-and-Safety_Logo-203x300-1.png\" alt=\"\" width=\"150\" height=\"300\" \/>","product_cfu":"","ingredients":"","regulations":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v28.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>HOWARU\u00ae Lpc-37\u00ae Probiotic for Stress Support | IFF<\/title>\n<meta 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