{"id":34104,"date":"2025-07-07T07:16:51","date_gmt":"2025-09-10T03:36:11","guid":{"rendered":"https:\/\/www.iff.com\/health-sciences\/our-products\/howaru-calm\/"},"modified":"2026-03-06T14:07:09","modified_gmt":"2026-03-06T19:07:09","slug":"howaru-calm","status":"publish","type":"our_products","link":"https:\/\/www.iff.com\/es\/health-sciences\/our-products\/howaru-calm\/","title":{"rendered":"HOWARU\u00ae Calm"},"content":{"rendered":"<div class=\"m-block  --bg-white --decor-dark-purple --pattern-v1 --decor --stats-type1 txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t            <div class=\"c-heading__pre\" >\n\t\t\t\tADVANTAGES            <\/div>\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Advantages of HOWARU\u00ae Calm\u200b<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Helping consumers support their mood health by:<\/p>\n<ul>\n<li>Promoting mental wellbeing\u200b and a relaxed state of mind\u200b<\/li>\n<li>Balancing and regulating feelings of stress<\/li>\n<li>Managing the mental response to stress\u200b<\/li>\n<\/ul>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t    <div class=\"c-block__btn\">\n\t\t\n\t\t\t\n\t\t    <\/div>\n\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white --decor-dark-purple --pattern-v3 --decor --stats-type2 txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">THE RAW POWER OF THE GUT-BRAIN CONNECTION IS REAL\u200b<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>The prevalence of stress and its effects continue to grow and negatively impact health and productivity. A clinical trial of HOWARU\u00ae Calm (HOWARU\u00ae Lpc-37\u00ae) demonstrated benefits in helping manage the psychological response to stress, promoting mental well-being, and helping balance and regulate perceived feelings of stress.\u200b<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/05\/231110_omni_iff_0921-1024x683.jpg\"  alt=\"231110_omni_iff_0921\" width=\"1024\" height=\"683\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt gb l-content-simple-1\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-heading text-left l-heading-v1\">\n\n\t\t\t<div class=\"l-heading__content\">\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p><small><strong>References: <\/strong><strong>1.<\/strong> Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. Vaccine. 2014;32:458-463; 2. Patterson E, Griffin SM, Ibarra A, Ellsiepen E, Hellhammer J. Lacticaseibacillus paracasei Lpc-37\u00ae improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial (the Sisu study). Neurobiol Stress. 2020;13:100277. doi: 10.1016\/j.ynstr.2020.100277; 3. Ding WK, Shah NP. Acid, bile and heat tolerance of free and microencapsulated probiotic bacteria. J Food Sci. 2007;72:M446-450; 4. Gibson GR, McCartney AL, Rastall RA. Prebiotics and resistance to gastrointestinal infections. Br J Nutr. 2005;93(Suppl. 1):S31-34.<\/small><\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-banner m-banner--small banner-contact order-default\" >\n\n\t\n\t\n\t<div class=\"m-banner__container container-fluid\" style='--columns-ratio: 100%;'>\n\t\t<div class=\"m-banner__media\">\n\t\t\t<picture class=\"m-banner__picture\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1440\" height=\"810\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc.jpg 1440w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-300x169.jpg 300w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-1024x576.jpg 1024w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-768x432.jpg 768w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-400x225.jpg 400w, https:\/\/www.iff.com\/wp-content\/uploads\/2025\/06\/csm_IFF_Contact-Us_Signpost_ea7dc82dcc-200x113.jpg 200w\" sizes=\"auto, (max-width: 1440px) 100vw, 1440px\" \/>\t\t\t\t\t\t\t<\/picture>\n\t\t<\/div>\n\n\t\t<div class=\"m-banner__inner container flex-left style-dark\">\n\n\t\t\t<div class=\"l-banner  l-gt-d l-gb-d\" style=\"\">\n\n\t\t\t\t\n<div class=\"l-banner__text\">\n\t    <div class=\"l-banner__inner text-left\">\n\n        <div class=\"c-heading -h2\">\n\t\t\t\n\t\t\t\t\t\t\t<h2  class=\"c-heading__title\"> How Can We Help?<\/h2>\t\t\t\n\t\t\t        <\/div>\n\n\t\t            <div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t<p>We\u2019d love to talk to you about how our microbiome and bioscience expertise can help you develop, manufacture and deliver solutions that enable people at all life stages to live healthier and happier lives. \u200b<\/p>\n            <\/div>\n\t\t\t\t\n\t\t    <\/div>\n\t\t    <div class=\"c-block__btn\">\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/contact-us\/\" target=\"_blank\" class=\"c-btn -normal -secondary has-icon icon-right\"><span class=\"c-btn__txt\">Contact Us<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t\n\t\t\t<a href=\"\/es\/health-sciences\/subscribe\/\" target=\"_blank\" class=\"c-btn -normal -secondary has-icon icon-right\"><span class=\"c-btn__txt\">Subscribe<\/span><span class=\"c-btn__ico\"><svg width=\"30\" height=\"30\" class=\"icon icon-lib-icon-arrow1\" aria-hidden=\"true\" role=\"img\"><use xlink:href=\"#lib-icon-arrow1\"><\/use><\/svg><\/span><\/a>\n\t\t\n\t\t\t<a href=\"https:\/\/www.linkedin.com\/showcase\/howaru-premium-probiotics\/\" target=\"_blank\" class=\"c-btn -normal -link has-icon icon-right\"><span class=\"c-btn__txt\">Follow Us<\/span><span class=\"c-btn__ico\"><svg fill=\"none\" height=\"21\" viewbox=\"0 0 23 21\" width=\"23\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path clip-rule=\"evenodd\" d=\"m2.75783 0c-1.66757 0-2.75783 1.05742-2.75783 2.44728 0 1.35918 1.05782 2.44676 2.69387 2.44676h.03163c1.70019 0 2.75825-1.08758 2.75825-2.44676-.03176-1.38986-1.05806-2.44728-2.72592-2.44728zm-2.488059 6.83477h4.874959v14.16473h-4.874994zm12.474729 2.05453s1.7633-2.3867 4.3933-2.3867c3.2071 0 5.6122 2.02465 5.6122 6.3755v8.1219h-4.8745v-7.5778c0-1.9042-.7056-3.2032-2.4696-3.2032-1.3468 0-2.1487.876-2.5013 1.7216-.1286.3028-.1605.7256-.1605 1.1491v7.9103h-4.87483v-14.16497h4.87523z\" fill=\"#99c8ec\" fill-rule=\"evenodd\"\/><\/svg><\/span><\/a>\n\t\t    <\/div>\n\t<\/div>\n\n\n\t\t\t<\/div>\n\n\t\t\t\t\t<\/div>\n\t<\/div>\n\n<\/div>","protected":false},"featured_media":34105,"template":"","product_health_benefits":[394],"product_type":[389],"class_list":["post-34104","our_products","type-our_products","status-publish","has-post-thumbnail","hentry","product_health_benefits-brain","product_type-probiotic"],"acf":{"full_name":"HOWARU\u00ae Calm","latin_name":"","short_description":"HOWARU\u00ae Calm is a probiotic for the gut-brain axis, that reduces perceived stress.","product_description":"HOWARU\u00ae <em>Lacticaseibacillus paracasei <\/em>Lpc-37\u00ae has been cited in more than 65 scientific publications, including more than 21 clinical trials. It has a long history of safe use, is well suited for intestinal survival, and has strong adhesion to intestinal cell lines and pathogen inhibition.\u00b9\u02d2\u00b2\r\n\r\nTailor-made products for the consumer you are targeting\r\nDemonstrated safe, well tolerated, clinically documented\u00b3\u02d2\u2074 probiotics\r\n\r\nDownload the handout to learn more.","pdf_file":34106,"product_information":"<img class=\"alignleft size-medium wp-image-24628\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/09\/IFF_Health-Sciences_HOWARU_Logo-300x129-1.png\" alt=\"\" width=\"300\" height=\"129\" \/>","product_cfu":"17B CFU | <a href=\"\/health-sciences\/our-products\/howaru-lpc-37\">HOWARU\u00ae <i>Lacticaseibacillus paracasei<\/i> Lpc-37\u00ae<\/a>","ingredients":"<ul><li><em>HOWARU\u00ae Lacticaseibacillus paracasei LPC-37\u00ae<\/em><\/li><\/ul>","regulations":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v28.6) - 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