{"id":18763,"date":"2025-03-27T16:08:02","date_gmt":"2025-03-27T20:08:02","guid":{"rendered":"https:\/\/www.iff.com\/?page_id=18763"},"modified":"2025-05-01T09:07:34","modified_gmt":"2025-05-01T13:07:34","slug":"solving-the-stability-challenge-for-laundry-enzymes","status":"publish","type":"page","link":"https:\/\/www.iff.com\/es\/home-care\/solving-the-stability-challenge-for-laundry-enzymes\/","title":{"rendered":"Solving the Stability Challenge for Laundry Enzymes"},"content":{"rendered":"<div class=\"m-banner m-banner--small  theme-v1 layout-v3 hero-simple has-overlay order-default\" >\n\n\t\n\t\n\t<div class=\"m-banner__container container-fluid\" style='--overlayOpacity: 45%;--columns-ratio: 75%;'>\n\n\t\t\t<div class=\"m-banner__media\">\n\t\t<picture class=\"m-banner__picture\">\n\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<source media=\"(min-width: 1500px)\" srcset=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/longform-stability-hero-gradient.jpg\">\n\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<source media=\"(min-width: 768px)\" srcset=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/longform-stability-hero-gradient-1024x533.jpg\">\n\t\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t<source media=\"(min-width: 300px)\" srcset=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/longform-stability-hero-gradient-768x400.jpg\">\n\t\t\t\n\t\t\t<img loading=\"lazy\" decoding=\"async\"   src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/longform-stability-hero-gradient.jpg\"  alt=\"Hero Image for Elegant Solutions: How IFF Solved the Stability Challenge for Laundry Enzymes\" width=\"1920\" height=\"1000\"\/>\n\t\t<\/picture>\n\t<\/div>\n\n\t\t<div class=\"m-banner__inner container flex-left style-dark\">\n\n\t\t\t<div class=\"l-banner  l-gt-d l-gb-d\" style=\"\">\n\n\t\t\t\t\n<div class=\"l-banner__text\">\n\t    <div class=\"l-banner__inner text-left\">\n\n        <div class=\"c-heading -h1\">\n\t\t\t\n\t\t\t\t\t\t\t<h1 style=\"color:#00416b;\" class=\"c-heading__title\">Elegant Solutions: How IFF Solved the Stability Challenge for Laundry Enzymes<\/h1>\t\t\t\n\t\t\t        <\/div>\n\n\t\t\t\t\n\t\t    <\/div>\n\t<\/div>\n\n\n\t\t\t<\/div>\n\n\t\t\t\n\t<div class=\"scroll-down sd-left\">\n        <span class=\"scroll-down__txt\">\n            SCROLL TO EXPLORE        <\/span>\n\t\t\t\t\t<span><\/span>\n\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-white txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Hero Ingredients<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Enzymes have earned their reputation as a hero ingredient in laundry detergents, breaking down specific stain types and saving energy by enabling washing at lower temperatures and shorter cycles. <\/p>\n<p>But enzymes also come with some practical challenges. These natural materials are proteins, which can be unstable and highly sensitive to environmental factors like temperature and pH, as well as other ingredients in detergent formulations like surfactants. <\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/shutterstock_631113926-edit-768x640.png\"  alt=\"Hero Ingredients - Enzymes, while highly effective in breaking down stains and saving energy in laundry detergents, face practical challenges due to their instability and sensitivity to environmental factors and other detergent ingredients.\" width=\"768\" height=\"640\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white parallax txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Stability is Crucial<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Because it can be a long and winding journey from the day a detergent formula leaves the factory floor to the moment a consumer adds their last measure to a load of laundry, maintaining enzyme stability is critical. It ensures these hero ingredients remain effective to the last dose. <\/p>\n<p>At IFF, we were the first to apply protein engineering to build better laundry enzymes. Today, we continue to advance our innovations to redefine industry standards, including efforts to deliver long-lasting performance with fewer ingredients.  <\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/shutterstock_2256514031-768x640.jpg\"  alt=\"Ensuring enzyme stability from production to the final wash is crucial for effective laundry detergents. At IFF, we lead in protein engineering to create superior enzymes, continually innovating for long-lasting performance with fewer ingredients.\" width=\"768\" height=\"640\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-dark-purple --pattern-v0 --decor --stats-type1 --pattern-color-white txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2 style=\"color:#ffffff;\" class=\"c-heading__title\">An existential problem: Proteases are self-destructive <\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Proteases are enzymes that break down proteins into smaller polypeptides and amino acids. They\u2019re a crucial part of attacking protein-based stains like milk, blood, and egg. However, they don\u2019t just break down proteins in food stains, they can also cannibalize other enzymes, including themselves.<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-video\">\n\n\t\t\t\t\t<div class=\"c-video__media c-video__primary c-image__primary\">\n\t\t\t\t\t\t\t\t\t\n\t\n\t<video muted playsinline disablepictureinpicture autoplay loop class=\"c-video\">\n\t\t<source src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/Spotlight_Video_V2.mp4\" type=\"video\/mp4\">\n\t<\/video>\n\n\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-dark-purple txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<blockquote><p>One of the core challenges is that proteases break down proteins, including other enzymes, into small fragments.<\/p><\/blockquote>\n<p>Many detergents also have an amylase and a mannanase that help breakdown starch and mannan-based stains, such as ice cream or chocolate pudding. You need all three enzymes to be stabilized against inactivation by proteolytic degradation. And that means having an enzyme with superior conformational stability, so the protease is not able to bind onto and then clip it or hydrolyze it.\u201d<\/p>\n<p><strong> TOM GRAYCAR<\/strong><br \/>\nTechnical Fellow, IFF<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"c-image__src\"  src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/quote1-Tom-768x722.png\"  alt=\"Tom Graycar, Technical Fellow at IFF\" width=\"768\" height=\"722\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white --decor-purple --pattern-v5 --decor --stats-type3 txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2 style=\"color:#93358d;\" class=\"c-heading__title\">Thinking About the Stability Problem in a New Way<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<blockquote><p>Enzymes that are easy to formulate with and stay active for longer are important for every entity along the supply chain. So, IFF\u2019s team of scientists knew they needed to apply their extensive experience with enzymes to tackle the stability problem.<\/p><\/blockquote>\n<p>The goal was to find a way to make a protease for liquid laundry detergents that is naturally stable. This breakthrough would not only keep detergents working at optimal effectiveness but also reduce or eliminate the need for additional chemical stabilizers in detergent formulations\u2014reducing cost and ingredient lists, which lowers environmental impact for detergent manufacturers.<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/shape-2.png\"  alt=\"Rewriting Rules of Enzyme Design Feature Image - Abstract image featuring wavy, fluid-like shapes in orange and blue colors against a light blue background.\" width=\"550\" height=\"550\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-blue-light parallax txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2  class=\"c-heading__title\">Do more with less<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>The key to finding a solution involved thinking about how to solve the problem in a way that delivered a long-term solution. The industry standard has been to add an additional chemical stabilizer \u2014 a protease inhibitor\u2014 to keep the protease from degrading itself or other enzymes in the formulation. But inhibitors need to be proven safe for the consumer and environment, and regulators can restrict or ban inhibitors. So, while many detergent manufacturers have had options to increase stability, they have lacked an ideal option when it came to creating formulas that would maintain their effectiveness.<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-video\">\n\n\t\t\t\t\t<div class=\"c-video__media c-video__primary c-image__primary\">\n\t\t\t\t\t\t\t\t\t\n\t\n\t<video muted playsinline disablepictureinpicture autoplay loop class=\"c-video\">\n\t\t<source src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/Text_Backdrop_V2.mp4\" type=\"video\/mp4\">\n\t<\/video>\n\n\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white parallax txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<blockquote><p>We needed to come up with an enzyme that could compete but didn&#8217;t rely on having that were restricted by regulators in the detergent formulation. Could protein engineering be used successfully to solve the problem? What we learned is that when you stabilize the conformational structure, an engineered enzyme can be robust enough <em>and <\/em>eliminate the need for stabilizers.\u201d<\/p><\/blockquote>\n<p><strong>THIJS KAPER<\/strong><br \/>\nSenior Lead Scientist, IFF<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-none is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"c-image__src\"  src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/quote2-Thijs-768x722.png\"  alt=\"Thijs Kaper, Senior Lead Scientist at IFF\" width=\"768\" height=\"722\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-dark-purple txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2 style=\"color:#ffffff;\" class=\"c-heading__title\">How do you build  an inherently  stable enzyme?<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>Finding the ideal solution involved unleashing the power of IFF\u2019s deep expertise in protein engineering and high-throughput screening.<\/p>\n<p>Enzymes have a so-called conformational structure, a defined 3-D arrangement, which can change in response to various factors impacting its catalytic efficiency and specificity.\u00a0 Proteins with conformationally less stable structures provide accessible areas for protease to bind to, clip the protein, and ultimately deactivate it.<\/p>\n<p>&nbsp;<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/IFF-lab-DSF7206-edit-768x800.jpg\"  alt=\"How to build inherently stable enzymes\" width=\"768\" height=\"800\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white parallax txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>The process of engineering a tighter, more stable conformation began with the IFF scientists taking advantage of both a ready selection of good starting enzymes and the complete data sets IFF has for these enzymes.<\/p>\n<p>It also involved testing thousands of possible changes they could make to improve the structure of the enzymes by using unique combinations of amino acid alterations. During their exploration of the thousands of potential mutations in the enzymes, the scientists focused not just on stability, but also superior cleaning performance and manufacturability.<\/p>\n<p>&nbsp;<\/p>\n<p>The result was the PREFRENZ\u00ae P 400 stable liquid enzyme, a protease, that delivers a combination of long-lasting stain removal performance with the type of enzymatic compatibility that allows for maximum flexibility when it comes to making new formulations.<\/p>\n<blockquote><p>At IFF we are very good at looking for the different properties we need in parallel: the manufacturability, the stability, and the cleaning power.\u201d<\/p><\/blockquote>\n<p><strong>TOM GRAYCAR<\/strong><br \/>\nTechnical Fellow, IFF<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-none is-video\">\n\n\t\t\t\t\t<div class=\"c-video__media c-video__primary c-image__primary\">\n\t\t\t\t\t\t\t\t\t\n\t\n\t<video muted playsinline disablepictureinpicture autoplay loop class=\"c-video\">\n\t\t<source src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/Mosaic-Tile-Light-Purple-1.mp4\" type=\"video\/mp4\">\n\t<\/video>\n\n\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-dark-purple txt-img-v2 l-content-2\"  >\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2 style=\"color:#ffffff;\" class=\"c-heading__title\">Boosting Enzyme Stability in Powder Detergents<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<blockquote><p>IFF scientists have also developed innovative technology to ensure the stability of enzymes in granular detergents.<\/p><\/blockquote>\n<p>With the ENZOGUARD platform they\u2019re harnessing advanced fluid bed coating technology, which creates multi-layer protection around an enzyme. This technique involves fluidizing substrate particles in a heated air stream while atomizing a liquid coating material into the particle flow.<\/p>\n<p>As the particles pass through the atomized liquid, droplets collect on the surface, spreading and drying to form a protective layer. By repeating this process, additional layers are added, creating a robust, multi-layer structure.<\/p>\n<p>&nbsp;<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/mosaic-1-768x1152.jpg\"  alt=\"mosaic 1\" width=\"768\" height=\"1152\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l parallax --bg-type-dark --scheme-grey txt-img-v2 l-content-2\"  style='background-color: #668d9d;'>\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-reverse\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p>This layering allows for more precise control over the formulation, where each layer can serve a specific function, like protection of the enzyme or controlled release. For example, stabilizers in one layer can help shield the enzyme from environmental stressors, while other layers may control moisture levels or optimize enzyme activity.<\/p>\n<p>The stability provided by fluid bed coating improves enzyme performance by ensuring enzymes remain active over extended periods, even under harsh conditions. And that means both retailers and consumers can trust that the enzyme activity will be consistent throughout the product\u2019s lifetime. With ENZOGUARD, the enzymes aren\u2019t simply better for longer. They also dissolve quickly, are well-distributed throughout the laundry product, and generally result in better overall performance<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-image\">\n\n\t\t\t\t\t<div class=\"c-image__media c-image__primary\">\n\t\t\t\t<img decoding=\"async\" class=\"c-image__src lazy\" loading=\"lazy\" src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/Stability-Visual-3-1-768x800.jpg\"  alt=\"Stability Visual 3\" width=\"768\" height=\"800\"\/>\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>\n\n\n<div class=\"m-block  gt-l gb-l --bg-white parallax txt-img-v2 l-content-2\"  style='color: #000000;'>\n\n\t\n\t\n\t<div class=\"m-block__container container\" style=\"\">\n\n\t\t<div class=\"l-dcbl l-dcbl-v1\">\n\n\t\t\t\n<div class=\"c-block order-default\" style=\"--c-block-radius:0px; --c-block-gl: 0%;--c-block-gr: 0%;--c-block-gt: 0%;--c-block-gb: 0%;--columns-ratio: 50%;\">\n\t<div class=\"c-block__col c-block__text text-left align-center\" style=\"--c-txt-gl: 0%; --c-txt-gr: 0%; --c-txt-gt: 0%; --c-txt-gb: 0%;\">\n\t\t<div class=\"c-block__inner\">\n\t\t\t<div>\n\n\t\t\t\t\n\t\t\t\t    <div class=\"c-heading -h2\">\n\t\t\n\t\t\n\t\t\t\t\t<h2 style=\"color:#0075cf;\" class=\"c-heading__title\">Performance, Naturally Better<\/h2>\t\t\n\t\t\n\t\t    <\/div>\n\t<div class=\"c-heading__description is-wysiwyg\">\n\t\t\t\t\t<p><strong>IFF\u2019s innovative work in the field of enzymes is setting a new standard in the laundry detergent industry, combining cutting-edge protein engineering and advanced formulation techniques to deliver more stable, longer-lasting products.<\/strong><\/p>\n<p>By working with nature, the scientists behind these enzyme solutions are delivering a host of benefits, transforming the way detergents perform while also reducing the need for additional stabilizers in detergent formulations. And these shorter, \u201ccleaner\u201d ingredient labels allow formulators to maintain their green credentials.<\/p>\n<p>But most importantly, nature is also the key to products that deliver superior performance without excessive costs, which means that stable enzymes make the formulator, the consumer, <em>and<\/em> the environment winners.<\/p>\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\t<\/div>\n\n\t            \n\t\t\t<\/div>\n\n            \n\t\t\t\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"c-block__col c-block__media\">\n\t\t\t<div class=\"c-image front-h-left front-v-center main-h-full main-v-center r-1x1 is-video\">\n\n\t\t\t\t\t<div class=\"c-video__media c-video__primary c-image__primary\">\n\t\t\t\t\t\t\t\t\t\n\t\n\t<video muted playsinline disablepictureinpicture autoplay loop class=\"c-video\">\n\t\t<source src=\"https:\/\/www.iff.com\/wp-content\/uploads\/2025\/03\/Mosaic_Mask_V2.mp4\" type=\"video\/mp4\">\n\t<\/video>\n\n\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t\n\t<\/div>\n\t\n\t\t\t<\/div>\n<\/div>\n\n\t\t<\/div>\n\n\t<\/div>\n\n\t\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":19,"featured_media":18791,"parent":10401,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-18763","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v28.6) - 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