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HOWARU® HN019™

HOWARU® HN019™

Bifidobacterium lactis HN019™

Image credits: © IFF, Finland, 2021 (FESEM imaging VTT)

HOWARU® Bifidobacterium lactis HN019™ has been consumed in dairy foods for decades and is well-studied for its probiotic properties in more than 180 scientific publications. It has been demonstrated to tolerate acidic conditions and shown to survive passage through the human intestine.¹⁻³ ​

Product Information:
  • 81 preclinical study publications
  • ~68 clinical trial publications

Health Benefits:
Digestive-HealthDigestiveEarly-Life-DevelopmentEarly Life DevelopmentImmune-HealthImmuneOral-HealthOral

HN019™ BLENDS

Learn more about IFF Health Sciences’ HN019™ blends.

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HOWARU® GI Complete

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HOWARU® Kids Digestive Health

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HOWARU® Protect 55+

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HOWARU® Smile

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HOWARU® Transit

HN019™ CLINICAL STUDIES & PUBLICATIONS

Mechanistic data suggests HN019™ may influence colonic motility, and multiple clinical trials with HN019™ alone or in combination with prebiotics or other probiotic strains have resulted in increased gut transit in persons with less frequent bowel movements positioned for adults as HOWARU® Transit and for kids as HOWARU® Kids Digestive Health.⁴⁻⁶HOWARU® Protect 55+ has also been shown to modulate immune function, particularly enhancing cellular immune activity in aging persons.⁷ It also offers oral health benefits as HOWARU® Smile offering a natural, alternative way to support healthy gum tissue and promote an overall healthy smile.

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Health Benefit Areas

Each strain’s health benefits are supported by recommended daily doses and peer-reviewed clinical studies.

Click on a Health Benefit to see more studies and learn more.

  1. Supporting Daily Dose: 2B and 17B CFU HN019™

    Study Reference: Waller PA, et al. Scand J Gastroenterol. 2011;46(9):1057-1064.

  2. Supporting Daily Dose: 5B CFU HN019™

    Study Reference: Hemalatha R, et al. EJNF. 2014; 4(4):325-341.

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Supporting Daily Dose: 5B CFU minimum HN019™

Study Reference: Miller LE, et al. Nutrients. 2017; 9(3):191.

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Supporting Daily Dose: 2B CFU HN019™

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References: 1. Gopal PK et al.; Nutrition Research. 2003; 2. Prasad J et al.; Intl Dairy J. 2013; 3. Wickens K et al.; J Allergy Clinical Immunology. 2008; 4. Dalziel Je et al.; Frontiers in Neuroscience. 2017; 5. Ibarra A et al.; Gut Microbes. 2017; 6. Waller PA et al.; Scandinavian J Gastroenterology. 2011; 7. Miller LE et al.; Nutrients. 2017.