IFF_HB_HS_HOWARU® Signature Strains

HOWARU® Signature Strains

Probiotic Quality You Can Feel

HOWARU® Signature Strains is a line of clinically mastered probiotic solutions from the leading industry experts at IFF Health Sciences.

The HOWARU® Difference

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High Performance

We boast more than 100 years of probiotic experience with over 700 scientific publications on probiotics.

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High Stability

Our products utilize efficient fermentation and concentration drying processes and patent-protected stability technology, which ensures perfectly active probiotics in optimal forms.

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High Functionality

Our products are formulated with only the best probiotic strains and combinations to ensure your product delivers the results you desire.

Discover HOWARU® Signature Strains

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B420®

​HOWARU® Bifidobacterium lactis​ B420® supports weight management and metabolic health.

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Bi-07®

HOWARU® Bifidobacterium lactis Bi-07® works in combination with other probiotic strains to supports overall digestive health in adults  and immune function in children.

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Bl-04®

HOWARU® Bifidobacterium lactis Bl-04® modulates the immune system to help maintain healthy respitory function and supports skin health.

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HN001™

HOWARU® Lacticaseibacillus rhamnosus HN001™ has been extensively studied across all life stages from early infancy through elderly years, and in pregnant and lactating women.

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HN019™

HOWARU® Bifidobacterium lactis​ HN019™ supports overall digestive health, immune function with aging, as well as oral health benefits.

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La-14®

HOWARU® Lactobacillus acidophilus La-14® supports women’s health in combination with HN0001™ and may impact both the innate and adaptive immune system.

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Lpc-37®

HOWARU® Lacticaseibacillus paracasei​ Lpc-37® helps manage the psychological response to stress and supports digestive health in children.

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NCFM®

HOWARU® Lactobacillus acidophilus NCFM® alone and in combination with other strains is well-studied for its benefit on digestive health in adults and immune health in children.

Our verify protocol: making HOWARU® signature strains

Strain Identification and Verification

Strain Identification

Sequenced and fully assembled the genome for every strain

Stability Assurance

Stability Assurance

Formulated and evaluated to ensure viability through end of shelf life.

Genetic Safety Screening

Genetic Safety Screening

Tested for virulence and toxigenic properties and the absence of antibiotic resistance transfer potential.

Regulatory Compliance

Regulatory Compliance

Generally Recognized As Safe (GRAS) or notified to FDA as New Dietary Ingredient (NDI) with no objection.

Toxicity Testing

Toxicity Testing

Tested for toxicity to confirm safety for human consumption

Quality Auditing

Manufacturing Quality

Consistently manufactured in the USA under FDA Good Manufacturing Practices. Quality systems audited by the National Science Foundation (NSF).

Survivability

Survivability

Tested for tolerance to stomach acid and bile salts.

Clinically Tested

Clinically Studied

Clinically studied for safety and efficacy.